Growth hormone-releasing peptide-6 (GHRP-6) is a small, six-mer peptide that stimulates the release of growth hormone by activating the ghrelin receptor found in the brain. Activating this receptor and increasing the levels of growth hormone within the body can modulate food intake and energy metabolism and also influences glucose and fat metabolism.
GHRP-6-induced metabolic changes result in less fat absorption, increased fat breakdown and stimulate the production of lean muscle mass. GHRP-6 can also be combined with additional growth hormone enhancers, such as GHRP2, sermorelin and CJC-1295. GHRP-2 is another peptide activator of the ghrelin receptor and has been shown to potently stimulate growth hormone secretion and increase appetite, leading to increased lean muscle growth . Combined dosing of sermorelin and GHRP-6 results in the enhanced production of human growth hormone and increased muscle mass, as does the combined dosing of CJC-1295 and GHRP-6.