PEGylated Mechano growth factor (MGF) can be a synthetically synthesized analog or a naturally produced hormone which is an mRNA splice variant of the insulin-like growth factor-1 (IGF-1) are said to induce muscle production and growth. However, another form of MGF has been developed, this is the MGF coated with polyethylene glycol (PEG). Coating the protein with PEG has a number of advantages. It has been previously reported that MGF rapidly degrades in the serum or tissue fluids, so to make its stable, synthetic MGF which is a 24 amino acid long MGF C-terminal peptide (NH2-YQPPSTNKNTKSQ(d)R(d)RKGSTFEEHK-NH2) was bound with PEG in the N-terminus. PEG – MGF is a long last MGF.